Sassuolo vs Lazio Prediction & Preview - Serie A
Sassuolo already have a 3-0 win over Lazio on the record this year, from the women's Serie A meeting in Rome on 25 April 2026. The men's sides settle their own version on Tuesday, and Sassuolo vs Lazio kicks off at 17:30 GMT on Tuesday, 27 October 2026 at the Mapei Stadium - Città del Tricolore in Reggio Emilia, with Alberto Aquilani's side 3 days on from a defeat at Como and Gennaro Gattuso's unbeaten in their last six.
- Fixture: Sassuolo v Lazio
- Competition: Serie A
- Date: Tuesday, 27 October 2026
- Kick-off: 17:30 GMT
- Venue: Mapei Stadium - Città del Tricolore, Reggio Emilia
- Match page: Sassuolo vs Lazio predictions
Sassuolo have not kept a clean sheet
Sassuolo have conceded two or more in 5 of their last 6 matches and have kept 0 clean sheets in that run. They have won 1, drawn 2 and lost 3, scoring 9 and conceding 13, and both sides have scored in 5 of the 6.
That is not a team short of goals. It is a team that cannot stop them. Sassuolo beat Juventus 3-2 at home on 13 September and then lost 2-4 away to Frosinone on 16 October, which tells you roughly everything about the shape of their season so far. Their most recent outing was a 0-2 defeat away to Como on 24 October.
Home is where what little evidence there is favours them: won 1 of 2 there, against 0 wins from 4 on the road.
Lazio have won five of their last six
Lazio have won 5 and drawn 1 of their last 6, scoring 15 and conceding 5, with 3 clean sheets. They have scored two or more in all 6 and conceded two or more in only 1.
The away record inside that run is the number that matters here: played 2, won 2, including a 3-0 at Juventus on 18 October. Three days before this fixture they beat Parma 2-1 at home. A side that scores freely and rarely leaks is a bad match for a defence in Sassuolo's current state.
Team news for Sassuolo vs Lazio
Sassuolo were without Fedde Leysen, Jay Idzes, Yeferson Paz, Daniel Boloca and Ismaël Koné for the Como game, Koné having broken a leg playing for Canada at the 2026 World Cup, according to The Stats Zone. For Lazio, Albert Guðmundsson is expected to be out until after the November international break with a shoulder problem picked up on international duty, while Nicolò Rovella and Adam Marušić have both been held back by muscle trouble, as reported by Football Italia; Danilo Cataldi has recovered and Matteo Cancellieri is back in training with the group, per The Laziali.
Sassuolo vs Lazio prediction
Lazio should beat Sassuolo in this Serie A fixture at the Mapei Stadium on Tuesday, 27 October 2026, and the likeliest route there is a game with goals in it rather than a controlled 1-0. Lazio have scored two or more in all 6 of their recent matches and won both away games in that stretch. Sassuolo have conceded two or more in 5 of 6 and failed to score only once, so they will probably get on the scoresheet without that being enough.
Our prediction: Sassuolo 1-2 Lazio
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