Inter vs Shakhtar Donetsk Prediction, Preview & Lineups

Shakhtar Donetsk travel to face Inter in the UEFA Champions League on Wednesday, 21 October 2026, kick-off 19:00 GMT.

Inter have the backing of their home support in this UEFA Champions League midweek clash. Shakhtar Donetsk arrive knowing a win here could be a significant statement.

Inter vs Shakhtar Donetsk Prediction

Calling the result in UEFA Champions League is never straightforward, but Inter are the narrow favourites, and Shakhtar Donetsk have the quality to make this a difficult afternoon for the hosts. Goals look likely in this UEFA Champions League encounter - both sides carry an attacking threat.

How to Predict Inter vs Shakhtar Donetsk

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Lineups

Inter and Shakhtar Donetsk lineups will be confirmed closer to the 19:00 GMT kick-off. Injury news and squad selection updates will shape both starting elevens.

UEFA Champions League Live Predictions on CalledItMate

CalledItMate covers UEFA Champions League with live in-play prediction markets throughout every match. The goalscorer market resets after every goal, giving you a new window to call the next scorer right up until the final whistle. The correct score market must be locked in before kick-off.

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